Other Forms of Neuromodulation

TNS (Trigiminal Nerve Stimulation) demonstration of the handheld device by Dr Mohamed Abdelghani at London TMS Centre

TMS is a form of non-invasive neuromodulation. Other forms of neuromodulation are also available in our centre and some of them are building strong evidence in scientific research to support their use in clinical practice in some cases.

At London TMS Centre we are passionate about exploring all forms of treatments and different neuromodulation modalities that can help our patients to recover and regain control of their lives.

However, it is important to know that none of these other forms of non-invasive neuromodulation has the same level of strong evidence to support it if compared to TMS. In other words none of these neuromodulation techniques is in the same league as TMS.

Our promise in London TMS Centre is that our experts will always discuss honestly and openly with you the pros and cons of these different techniques in order to help you to make an informed decision about your treatment.

Other neuromodulation treatment modalities available at our centre are:

VNS (Vagus Nerve Stimulation)

Nurify Medical is proud to be the first private clinic in the UK to offer VNS to patients suffering with depression.

VNS received the European CE Mark in 2003 as treatment for Treatment Resistant Depression (TRD). In the USA the FDA cleared the first VNS device for the treatment of recurrent or chronic depression in 2005.

VNS is an invasive neuromodulation treatment modality. Treatment with VNS involves having a surgical procedure. During the surgery a pacemaker-like device is implanted in the patient’s left upper chest wall.  The device is connected to the left vagus nerve in the neck.

The exact mechanism of action of VNS is not fully known. However, because of how the vagus nerve is connected to different parts of the brain by stimulating the vagus nerve we can alter some chemicals in the brain. Such as, increasing noradrenergic and serotonergic neurotransmission both of which are involved in depression.

The safety of using VNS has been well established for years given that it is a recommended treatment for epilepsy with more than half a million patients implanted with the device.

In Nurify Medical we have formed a collaboration with one of the top neurosurgical teams in the UK. Our VNS will have their surgeries done at The London Clinic under supervision of Dr Erlick Pereira (Consultant Neurosurgeon).

Our Consultant Psychiatrists will be happy to discuss the pros and cons of VNS and if it is the right treatment for you.

TNS (Trigiminal Nerve Stimulation)

TNS is a non-invasive form of neuromodulation. It uses a handheld device (Monarch®) that individuals can use at home. The device is connected with thin wires to an adhesive patch that is placed over the patient’s forehead. Patients are usually advised to have the stimulation from the device for 8 hours during sleep.

Monarch® device received the European CE Mark in November 2015 and FDA clearance in April 2019 as a medical device for the treatment of paediatric ADHD.

TNS has been tested as a possible treatment for a number of psychiatric and neurological conditions, such as, depression, Attention Deficit Hyperactivity Disorder (ADHD), Post Traumatic Stress Disorder (PTSD), epilepsy and Traumatic Brain Injury (TBI).

Some of these studies showed very good and promising clinical results in treating mental health conditions such as; depression and ADHD.

Dr Abdelghani has experience in using TNS and he was one of the first Psychiatrists to introduce this new treatment modality to patients in the UK.

Flow (tDCS – transcranial Direct Current Stimulation)

tDCS is a non-invasive and non-pharmacological form of neurostimulation. The Flow tDCS device is Bluetooth controlled and managed through the Flow depression app. It is available through a medical device that can be used at home. The flow headset has European CE mark.

tDCS has been used in research settings for a number of years. Results of some of these studies are quite promising and indicates that tDCS can be a possible treatment option for patients suffering with depression.

tDCS works by delivering a weak direct electrical current to specific areas of brain via electrodes placed on the scalp. It helps the cortex of the brain become more easily excited.

Dr Abdelghani is happy to discuss with patients the pros and cons of different neuromodulation treatment modalities, including Flow tDCS.

lady using flow tDCS bluetooth device to manage depression at home

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